Catalogue

Background
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.

Synonyms: Sal-like protein 4, Zinc finger protein 797, Zinc finger protein SALL4

Source

Immunogen: Synthetic peptide derived from the human SALL4 protein

Product

Product Form: Affinity Purified

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Antigen Immunoaffiinity Purification

Concentration: See vial for concentration

Applications
Antibody can be used for Immunohistochemistry (2-4 µg/ml) and Western blotting (1-2 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting

Positive Control: Human testis

Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio​ accepts no liability for any inaccuracies or omissions in this information.

References
1. Ma, Y., et al. ‘SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice.’ Blood, 108, 2726-2735 (2006) 2. Kohlhase, J., et al. ‘Okihiro syndrome is caused by SALL4 mutations.’ Hum. Mol. Genet., 11, 2979-2987 (2002) 3. Yang, F., et al. ‘Sumoylation is important for stability, subcellular localization, and transcriptional activity of SALL4, an essential stem cell transcription factor.’ J. Biol. Chem., 287, 38600-38608 (2012)

Protein Reference(s)

Database Name: SwissProt

Accession Number: Q9UJQ4

Species Accession: Human

Safety Datasheet(s) for this product: