Rabbit anti Human APM2 (CT)Catalog number: X2385P
Antigen Immunoaffinity Purified Polyclonal
APM2 is an ~8kDa protein which until recently was found only in the EST data base but never as an expressed protein. APM2 has since been shown to be associated with cisplatin resistance in cell lines. APM2 is not found in cisplatin sensitive cell lines. These data implicate APM2 in the development of cisplatin resistance in tumor cells.
Synonyms: Adipose most abundant gene transcript 2 protein, apM-2, APM2, C10orf116
Immunogen: Synthetic peptide derived from human APM2 protein
Product Form: Affinity Purified
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Antigen Immunoaffiinity Purification
Concentration: Lot specific, see vial
Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Functional Analysis: Western Blotting
Positive Control: Adipose tissue, cornea and liver.
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.
1. Scott, B.J., et al. APM2 is a novel mediator of cisplatin resistance in a variety of cancer cell types regardless of p53 or MMR status. Int. J. Cancer 2009, 125, 1193-1204
Database Name: UniProt
Accession Number: Q15847
Safety Datasheet(s) for this product:
|Immunohistochemical staining of normal human liver tissue using APM2 antibody (Cat. No. X2385P) at 15 µg/ml.
Immunohistochemical staining of normal human liver tissue using APM2 antibody (Cat. No. X2385P) at 15 µg/ml.