Catalogue
Mouse anti Human p19 - ink4d
Catalog number: C165M| Clone | DCS-100 |
| Isotype | IgG1 |
| Product Type |
Monoclonal Antibody |
| Units | 100 µg |
| Host | Mouse |
| Species Reactivity |
Human |
| Application |
Immunohistochemistry Immunoprecipitation Western Blotting |
Background
The immunogen for the anti-h-p19 was a his-tagged recombinant full length p19 protein recognizing a 19kD protein. The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.
Synonyms: hp19; p19 ink4d; CDKN2D; Cyclin-dependent kinase 4 inhibitor D
Source
Immunogen: A his-tagged recombinant full length p19 protein recognizing a 19kD protein
Product
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Applications
Applications: Western Blot, Immunoistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)
Functional Analysis: Western Blotting
Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Product Stability: See expiration date on vial
Shipping Conditions: Room Temperature
Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
References
1) H. Hirai, et. al. (1995) Mol. Cell. Biol. (15) 2672-2681
2) JIRINA BARTKOVA, MINNA THULLBERG, PREMYSL SLEZAK, EDGAR JARAMILLO, CARLOS RUBIO, LARS H. THOMASSEN, and JIRI BARTEK. Aberrant Expression of G1-Phase Cell Cycle Regulators in Flat and Exophytic Adenomas of the Human Colon. GASTROENTEROLOGY 2001;120:1680–1688
Protein Reference(s)
Database Name: UniProt
Accession Number: P55273 (Human)
Species Accession: Human
Safety Datasheet(s) for this product:
| NM_Sodium Azide |